BPC-157 5mg & 10mg

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BPC 157 is a penta-decapeptide composed of 15 amino acids. It is a partial sequence of the body protection compound (BPC) that was discovered in and isolated from human gastric juice. Animal studies have shown it to accelerate the healing of many different wounds, including muscle, tendon and damaged ligaments. Additionally, BPC 157 has shown to protect organs and aids in the prevention of gastric ulcers.

BPC-157 acts systemically in the digestive tract to combat leaky gut, IBS, gastro-intestinal cramps, and Crohn’s disease. This peptide has been known to exhibit analgesic characteristics. Research has shown its ability to help skin burns heal at a faster rate by increasing blood flow to damaged tissues. BPC-157 significantly accelerates reticulin and collagen formation as well as angiogenesis together with stimulation of macrophages and fibroblasts infiltration representing a potential therapeutic tool in wound healing management.

BPC-157 10mg research peptide is showing good results in wound healing. It is not for human consumption. BPC-157 dosage works fast to heal muscle, tendons and ligaments, and bones. In addition, it can treat ulcers, protect organs, IBS, gastro-intestinal cramps, and Crohn’s disease.  For the best BPC-157 for sale buy here now.

 

PRODUCT USAGE WARNING : This PRODUCT IS INTENDED AS A RESEARCH CHEMICAL ONLY. This designation allows the use of research chemicals strictly for in vitro testing and laboratory experimentation only. All product information available on this website is for educational purposes only. Bodily introduction of any kind into humans or animals is strictly forbidden by law. This product should only be handled by licensed, qualified professionals. This product is not a drug, food, or cosmetic and may not be misbranded, misused or mislabled as a drug, food or cosmetic.

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Description

BUY BPC-157 PEPTIDE FOR SALE ONLINE

What Is BPC-157?

BPC-157, short for Body Protection Compound-157, is a derivative of body protection compound (BPC). BPC is a protein found naturally in the human digestive tract. It plays a significant role in protecting the lining of the gastrointestinal tract from damage, promoting healing, and encouraging blood vessel growth.

Synthetic BPC-157, a pentadecapeptide comprising 15 amino acids isolated from the much larger BPC protein, has been found to retain many of the healing properties of its parent molecule. In particular, BPC-157 has been shown to have effects on:

  • Wound healing
  • Blood vessel growth
  • The coagulation cascade
  • Nitric oxide generation
  • Immune system function
  • Gene expression
  • Hormone regulation (particularly in the gastrointestinal nervous system)

BPC-157 Peptide For Sale online only at USA Peptide Store where you can buy USA Research Peptides online. Shop over 100 research peptides online now for fast shipping and the best deal! Buy in bulk and Save! USA Peptide Store Your #1 Trusted USA Research Peptides Supplier.

If this product does not meet your needs or interests, you may want to look at BPC-157, TB-500 10mg (Blend) Peptide. Please visit this link for further information on our Other Peptides


BPC-157 Peptide Structure

bpc-157 peptide structure

Source: PubChem

Sequence: Gly- Glu-Pro-Pro-Pro-Gly-Lys-Pro-Ala-Asp-Asp-Ala-Gly-Leu-Val
Molecular Formula: C62H98N15O22
Molecular Weight: 1419.556 g/mol
PubChem CID: 108101


BPC-157 Peptide Research

1. BPC-157 and Wound Healing

The natural function of BPC in the GI tract is to maintain the integrity of the mucosal barrier that protects underlying tissues from the harmful actions of gastric acid, bile, and other compounds necessary for digestion and absorption of nutrients from food. At least part of this function is mediated through the recruitment of fibroblasts. BPC-157 has a dose-dependent effect on the spread of fibroblasts in culture and in vivo, causing the cells to both proliferate and migrate faster. Fibroblasts are integral to wound healing as they are the cells responsible for laying down extracellular matrix proteins like collagen, fibrin, elastin, and more.

2. Vascular Growth and Collateralization

BPC-157 is a potent angiogenic factor, increasing the rate at which endothelial cells (the cells that line blood vessels) proliferate and grow. Research in rats shows that the peptide substantially increases the rate of collateral blood vessel growth in the setting of ischemia. While this effect has been primarily observed in the GI tract, there is evidence for similar benefit in cardiovascular, neurological, and muscle tissues, suggesting that BPC-157 may be used as both a therapy in the setting of stroke and heart attack as well as a probative peptide for understanding how to promote healing following ischemic injury. Studies in chicken embryos suggest that at least part of the mechanism by which BPC-157 promotes vascular growth is through the stimulation of VEGFR2, a cell surface receptor active in the nitric oxide signaling pathway. VEGFR2 is thought to play an important role in endothelial cell growth, proliferation, and longevity.

BPC-157 concentration versus vascular endothelial cell growth

BPC-157 concentration versus vascular endothelial cell growth
Source: PubMed

Cell culture research has effectively demonstrated vascular “running” secondary to BPC-157 administration. Vascular running is the process by which vessels grow toward an area of injury or around an area of vascular occlusion to reestablish blood flow to distal tissue and protect cell function. This particular function of BPC-157 may make it possible to develop an effective oral treatment for slow-growing arterial occlusions, such as are seen in atherosclerotic heart disease. This area of research may one day render unnecessary surgical interventions such as stenting, coronary artery bypass grafting, and more.

3. BPC-157 and Tendon Healing

Given its roles in fibroblast recruitment and blood vessel growth, it should come as no surprise that BPC-157 has shown positive findings in animal models of tendon, ligament, bone, and other connective tissue injuries. Tendon and ligament injuries are slow to heal, in large part, due to poor blood supply to these tissues. Poor blood supply slows the rate at which fibroblasts and other wound-healing cells can reach the area of injury and, ultimately, restricts the overall level of repair that can take place. Both in vitro and in vivo research involving rat tendons has shown that BPC-157 promotes collateralization and boosts fibroblast density in the setting of tendon, ligament, and bone injury. This research indicates that BPC-157 is more effective than bFGF, EFG, and VGF hormones in promoting healing in these tissues.

Experiments using FITC-phalloidin staining have revealed that BPC-157 is a potent stimulator of F-actin formation in fibroblasts. F-actin is critical to cell structure and function, playing an important role in cell migration. Analysis via western blotting indicates that BPC-157 increases phosphorylation of paxillin and FAK proteins, which are critical proteins in the cell migration pathway.

4. Antioxidant Properties

Research in rats has shown that BPC-157 can neutralize certain oxidative stress markers like nitric oxide and malondialadehyde (MDA). This makes BPC-157 a powerful antioxidant, a property of the peptide that is further supported by research showing that it can reduce the production of reactive oxygen species in the gastrointestinal tract. Research investigating whether modified lactococcus lactis bacteria can deliver BPC-157 to the GI system shows that the bacteria increases levels of the peptide dramatically in cell culture.

5. BPC-157 and Drug Side Effects

Often, the limiting factor in medical pharmaceutical use is side effects. NSAIDs, like ibuprofen, for instance, cannot be used for long periods of time because they increase gastric bleeding as well as the risk for heart attack. The ability to counteract side effects while leaving desired effects intact is a holy grail of modern medical research as it would improve therapeutic benefits for a number of drugs. BPC-157 has been found to counteract side effects of NSAIDs, medications used in psychiatric conditions, and a number of heart medications.

Celecoxib-induced gastric lesions (black) in rats treated with BPC-157, saline (control), L-NAME, and L-arginine.

Celecoxib-induced gastric lesions (black) in rats treated with BPC-157, saline (control), L-NAME, and L-arginine.
Source: World Journal of Gastroenterology

It should come as no surprise that BPC-157 helps to prevent many of the GI side effects that certain drugs are known for, but it is less intuitive that the peptide also protects against side effects in the brain, heart, and other tissues. Research in rats, for instance, shows that BPC-157 can protect against QTc prolongation in the heart, a condition that can lead to serious and even fatal arrhythmias. QTc prolongation is caused by drugs used to treat diabetes, schizophrenia, and other psychiatric conditions . Similarly, BPC-157 has been shown to prevent other side effects of psychiatric medications, including severe side effects like catalepsy and somatosensory disturbance. This latter benefit may make it possible to more adequately treat psychiatric conditions, which are notoriously difficult to treat, in part because patients often discontinue their medications secondary to severe side effects.

6. BPC-157 and Bees

Colony collapse disorder (CCD) is a syndrome in which entire colonies of honey bees experience rapid decline and, eventually, complete destruction. Causes of the condition are not fully defined, but at least part of the problem can be contributed to an infection in honey bee guts by the fungus Nosema ceranae. By supplementing the food that honey bees eat with BPC-157, researchers have shown a reduction in the damage the fungus causes in honey bee GI tracts and a concomitant increase in hive survival rates. These trials were carried out in natural field settings and offer the first significant oral treatment for reducing the impact of CCD on the most important pollinator for most food crops.


Future BPC-157 Research

BPC-157 is under active investigation in a number of cell culture and animal models. The peptide shows a great deal of promise not just as a therapeutic agent for promoting wound healing and regulating vascular growth, but as a tool for investigating these processes to better understand their control. Research using BPC-157 has the potential to shed a great deal of light on angiogenesis in particular, a process that is not only critical to wound healing, but that plays extensive roles in growth, cancer development, and embryogenesis.

BPC-157 exhibits minimal side effects, moderate oral and excellent subcutaneous bioavailability in mice. Per kg dosage in mice does not scale to humans. BPC-157 Peptide for sale at USA Peptide Store is limited to educational and scientific research only, not for human consumption. Only buy BPC-157 if you are a licensed researcher.

Buy Wholesale BPC-157 Peptide From USA Peptide Store

At USA Peptide Store, our research peptides are of the highest purity and pharmaceutical grade. Our BPC-157 Peptide comes in 5mg and 10mg. We’re passionate about our products, and we always strive to provide our customers with the best in both selection and quality. All of the products we provide are tested to verify authenticity and purity, so you can conduct your research with confidence.

Searching for BPC-157 Peptide for sale? Look no further! Our online peptide store offers a wide range of BPC-157 Peptide, perfect for your research needs. Whether you’re in the United States, Australia, Canada, Germany, Sweden, France, Turkey, Thailand, Italy, Netherlands or the United Kingdom, we have you covered. We provide fast and secure shipping to multiple countries, ensuring that you receive your order conveniently and on time. Purchase BPC-157 Peptide that are now available for sale and in stock. With our competitive prices and extensive inventory, you can trust us to be your reliable source for BPC-157 5mg & 10mg.

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10 mg, 5 mg

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