Each Capsule contains 5-Amino-1MQ 50mg, NMN 50mg, JBSNF 5mg 5-amino-1MQ is a small molecule that blocks the activity of the enzyme called nicotinamide N-methyltransferase (NNMT). By blocking NNMT, 5-amino-1MQ stimulates an increase in NAD+, a cofactor that is central to cellular metabolism, thereby increasing metabolic rate and activating a gene called sirtuin-1 (SIRT1). SIRT1 is also known as the "longevity gene" because of its role in reducing the risk of diabetes, obesity, metabolic syndrome, atherosclerosis and other forms of cardiovascular disease, kidney disease, liver disease, neurodegeneration, and cancer. Longevity, Performance & Obesity Research (60 Capsules) (5-Amino-1MQ, NMN, JBSNF). A research peptide blend that can significantly improve metabolic regulation and lower body weight. Studies with this supplement have also found it to be effective in increasing energy, insulin sensitivity, eye function and lipid profile. NMN (Nicotinamide mononucleotide) Nicotinamide mononucleotide (NMN) is a unique form of vitamin B3 that gets converted into Nicotinamide Adenine Dinucleotide (NAD+). NAD+ declines with age and is an essential coenzyme for a number of enzymes involved with energy production and cellular repair. The sirtuin family are among these NAD+ dependent enzymes and act as master switches of metabolism and regulators of aging. Preliminary research suggests NMN supports synthesis of NAD+ in tissues, supporting cellular function and longevity, energy metabolism, aerobic capacity and glucose homeostasis. Research has shown NMN to decrease age-associated body weight gain, improve energy metabolism, insulin sensitivity and plasma lipid profile, enhanced eye function and other pathophysiologies. JBSNF-000088 inhibits NNMT activity, reduces MNA levels and drives insulin sensitization, glucose modulation and body weight reduction in animal models of metabolic disease. In mice with high fat diet (HFD)-induced obesity, JBSNF-000088 caused a reduction in body weight, improved insulin sensitivity and normalized glucose tolerance to the level of lean control mice. These three compounds affect everything from energy metabolism to cellular performance and aging. They primarily by affecting levels of NAD, the expression of GLUT-4 receptors, the activity of the NNMT enzyme and the production of molecules known as sirtuins. By increasing levels of NAD and decreasing the activity of NNMT, these molecules work together to improve cellular metabolism, enhance weight loss, and improve glucose control. Further benefits of the synergy between these compounds are seen in cellular aging, where increased levels of NAD help stem cells to survive and thrive. This provides a pool of healthy cells that can readily take the place of those that are worn or damaged, leading to improved tissue function and decreasing the effects of aging. By combining these three compounds, it might be possible to drastically alter energy metabolism for the better while simultaneously boosting anti-aging, anti-inflammatory, and anti-apoptosis activity in cells.   PRODUCT USAGE WARNING : This PRODUCT IS INTENDED AS A RESEARCH CHEMICAL ONLY. This designation allows the use of research chemicals strictly for in vitro testing and laboratory experimentation only. All product information available on this website is for educational purposes only. Bodily introduction of any kind into humans or animals is strictly forbidden by law. This product should only be handled by licensed, qualified professionals. This product is not a drug, food, or cosmetic and may not be misbranded, misused or mislabled as a drug, food or cosmetic.

Each capsule contains 500mcg Stable BPC-157, 500mcg KPV, 400mg PEA, 400mg Tributyrin BPC-157 is a synthetic derivative of naturally occurring body protection compound (BPC), known for its anti-inflammatory and wound healing properties. BPC-157 is stable in human gastric juice, during prolonged storage, and when exposed to UV light. It possesses enhanced oral bioavailability (greater than 90%). Animal studies indicate that BPC157 may significantly improve gastrointestinal healing from ulcers, colitis, irritable bowel syndrome, and other inflammatory bowel diseases. KPV is an anti-inflammatory peptide that has potential to help decrease inflammation in a wide range of intestinal diseases such as Crohn's disease and Ulcerative Colitis. It decreases the inflammatory response by inhibiting proinflammatory cytokine synthesis and secretion. KPV has been shown to stop the proinflammatory mechanisms in both intestinal epithelial cells and immune cells. KPV has shown promise in the case of Inflammatory Bowel Diseases through inhibited immune responses. KPV has also been shown to support healing of the mucosal lining of the gut which helps to stabilize Ulcerative Colitis. In one study KPV was given to mice with Ulcerative Colitis. These mice experienced significant improvements in body weight, colon length and disease symptoms. PEA is a fatty acid amide molecule involved in a variety of cellular functions in chronic pain and inflammation. It has been shown to have neuroprotective, anti-inflammatory, anti-nociceptive (antipain) properties. The most important and promising indications for PEA are linked to neuropathic and chronic pain and inflammation such as gastro-intestinal inflammation, diabetic neuropathic pain, sciatic pain, CRPS, pelvic pain and entrapment neuropathic pain. Tributyrin is a natural triglyceride that decreases inflammatory signaling by TNF-alpha, interleukin-1B, and interleukin-6. Studies show that Tributyrin regulates tight junctions to bolster intestinal barrier function. This may help to reduce the number of inflammatory particles that cross from the intestinal lumen (where food is) into the body, thereby preventing gut inflammation from starting. It also boosts expression of vitamin D3 receptors. Studies show that Tributyrin regulates tight junctions to bolster intestinal barrier function.Tributyrin may improve immune function, increase mucus production in the GI tract, and accelerate gastrointestinal wound healing. Synergy Between BPC 157, KPV, PEA, and Tributyrin Individually, BPC 157, PEA, Tributyrin, and KPV offer substantial benefits in fighting inflammation, particularly of the GI tract. In combination, the four act synergistically to regulate inflammation via several different but overlapping pathways. Together, these four compounds help produce enhanced anti-inflammatory effects by: • reducing cyclooxygenase-2 signaling, • substantially reducing TNF-alpha levels, • activating nuclear transcription factors responsible for controlling the immune system, • improving gastric mucous secretion and function • enhancing intestinal barrier function.   PRODUCT USAGE WARNING : This PRODUCT IS INTENDED AS A RESEARCH CHEMICAL ONLY. This designation allows the use of research chemicals strictly for in vitro testing and laboratory experimentation only. All product information available on this website is for educational purposes only. Bodily introduction of any kind into humans or animals is strictly forbidden by law. This product should only be handled by licensed, qualified professionals. This product is not a drug, food, or cosmetic and may not be misbranded, misused or mislabled as a drug, food or cosmetic.